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What drugs are used to treat Crohn’s disease and ulcerative colitis (UC)?

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For severe disease Crohn’s disease and ulcerative colitis, you may need drugs that work on the immune system. These include:

  • 6-mercaptopurine (6-MP, Purinethol, Purixan)
  • adalimumab (Humira)
  • adalimumab-atto (Amjevita), a biosimilar to Humira
  • azathioprine (Azasan, Imuran)
  • certolizumab pegol (Cimzia)
  • cyclosporine
  • golimumab (Simponi, Simponi Aria)
  • infliximab (Remicade)
  • infliximab-abda (Renflexis),a biosimilar to Remicade
  • infliximab-dyyb (Inflectra), a biosimilar to Remicade
  • methotrexate (Rheumatrex, Trexall)
  • natalizumab (Tysabri)
  • ustekinumab (Stelara)
  • vedolizumab (Entyvio)

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. March 2005. Inflammatory Bowel Diseases,

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2018

SOURCES:

Cleveland Clinic: “Why You Should Pay Attention to Chronic Inflammation.”

Crohn’s and Colitis Foundation of America: “What are Crohn’s & Colitis?” "Crohn’s Diagnosis & Testing." “Diagnosing Crohn's Disease and Ulcerative Colitis” “Surgery for Crohn’s Disease & Colitis?”

FDA. “FDA approves Inflectra, a biosimilar to Remicade.” “FDA approves Amjevita, a biosimilar to Humira.”

Itzkowitz, S. March 2005. Inflammatory Bowel Diseases,

Mayo Clinic: “Inflammatory Bowel Disease.”

Medscape: “Ulcerative Colitis Differential Diagnoses.”

PubMedHealth: “Colon (Bowel.)”

UCLA Division of Digestive Disorders: “Ulcerative Colitis vs. Crohn's Disease.”

UpToDate: “Patient information: Ulcerative colitis (Beyond the Basics).” “Patient information: Crohn Disease (Beyond the Basics)." "Clinical manifestations, diagnosis and prognosis of Crohn disease in adults." “Colorectal cancer surveillance in inflammatory bowel disease.”

Reviewed by Melinda Ratini on September 4, 2018

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How common is it to go into remission if you have ulcerative colitis or Crohn's disease?

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