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How do anti-depressants treat irritable bowel syndrome (IBS)?

ANSWER

Some depression meds can treat the mood disorder and some of the symptoms of irritable bowel syndrome (IBS). However, they're used in different ways for each condition, so it's important to talk with your doctor to learn how you should take them.

Even people with irritable bowel syndrome who aren’t depressed can get relief from antidepressants. The drugs can help block how the brain processes pain.

SOURCES: 

Lydiard RB. , 2001.  J. Clin Psychiatry

Philip Schoenfeld, MD, MSEd, MSc, co-author of American College of Gastroenterology's "Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome in North America." 

Jeanine Blackman, MD, PhD, medical director of the University of Maryland Center for Integrative Medicine. 

Jonathan Gilbert, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM). 

The National Center for Complementary and Alternative Medicine. 

Mayo Clinic: "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD." 

Fadgyas-Stanculete M., , 2014.  Journal of Molecular Psychiatry

Medline Plus: "Amitriptyline" and "Desipramine."

Reviewed by Minesh Khatri on March 25, 2018

SOURCES: 

Lydiard RB. , 2001.  J. Clin Psychiatry

Philip Schoenfeld, MD, MSEd, MSc, co-author of American College of Gastroenterology's "Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome in North America." 

Jeanine Blackman, MD, PhD, medical director of the University of Maryland Center for Integrative Medicine. 

Jonathan Gilbert, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM). 

The National Center for Complementary and Alternative Medicine. 

Mayo Clinic: "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD." 

Fadgyas-Stanculete M., , 2014.  Journal of Molecular Psychiatry

Medline Plus: "Amitriptyline" and "Desipramine."

Reviewed by Minesh Khatri on March 25, 2018

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Which antidepressants can help irritable bowel syndrome (IBS) symptoms?

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