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What antidepressants are used to treat IBS with constipation (IBS-C)?

ANSWER

Your doctor may prescribe you a low dose of anti-depressants for your IBS. This doesn't necessarily mean that you are depressed. Anti-depressants can block the brain's perception of pain in the gut.

For IBS-C, your doctor may prescribe small doses of an SSRI (selective serotonin reuptake inhibitor) antidepressant, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft). Their side effects may include nausea, loss of appetite, and diarrhea.

SOURCES:

Philip Schoenfeld, MD, professor of medicine, University of Michigan.

Jeanine Blackman, MD, PhD, Bethesda, MD.

The National Center for Complementary and Alternative Medicine: "Acupuncture."

Mayo Clinic: "Irritable Bowel Syndrome."

About.com: "Herbs and Supplements for IBS."

Medscape: "Probiotics Significantly Reduce Symptoms of IBS, Ulcerative Colitis," "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD."

FDA.

Harvard Health Publications: "Understanding and treating an irritable bowel."

Reviewed by Minesh Khatri on August 30, 2019

SOURCES:

Philip Schoenfeld, MD, professor of medicine, University of Michigan.

Jeanine Blackman, MD, PhD, Bethesda, MD.

The National Center for Complementary and Alternative Medicine: "Acupuncture."

Mayo Clinic: "Irritable Bowel Syndrome."

About.com: "Herbs and Supplements for IBS."

Medscape: "Probiotics Significantly Reduce Symptoms of IBS, Ulcerative Colitis," "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD."

FDA.

Harvard Health Publications: "Understanding and treating an irritable bowel."

Reviewed by Minesh Khatri on August 30, 2019

NEXT QUESTION:

What antispasmodic drugs are used to treat IBS with constipation (IBS-C)?

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