PREVIOUS QUESTION:

 

NEXT QUESTION:

 

Which antidepressants can help irritable bowel syndrome (IBS) symptoms?

ANSWER

  • The American College of Gastroenterology says two types of antidepressants can help irritable bowel syndrome (IBS) symptoms: Tricyclic antidepressants, like amitriptyline (Elavil, Vanatrip), desipramine (Norpramin), or nortriptyline (Pamelor)
  • Selective serotonin reuptake inhibitors (SSRIs), like citalopram (Celexa), paroxetine (Paxil), or sertraline (Zoloft)

However, experts say they need more research to fully understand how safe and effective the drugs are for people with IBS.

SOURCES: 

Lydiard RB. , 2001.  J. Clin Psychiatry

Philip Schoenfeld, MD, MSEd, MSc, co-author of American College of Gastroenterology's "Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome in North America." 

Jeanine Blackman, MD, PhD, medical director of the University of Maryland Center for Integrative Medicine. 

Jonathan Gilbert, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM). 

The National Center for Complementary and Alternative Medicine. 

Mayo Clinic: "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD." 

Fadgyas-Stanculete M., , 2014.  Journal of Molecular Psychiatry

Medline Plus: "Amitriptyline" and "Desipramine."

Reviewed by Minesh Khatri on March 25, 2018

SOURCES: 

Lydiard RB. , 2001.  J. Clin Psychiatry

Philip Schoenfeld, MD, MSEd, MSc, co-author of American College of Gastroenterology's "Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome in North America." 

Jeanine Blackman, MD, PhD, medical director of the University of Maryland Center for Integrative Medicine. 

Jonathan Gilbert, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM). 

The National Center for Complementary and Alternative Medicine. 

Mayo Clinic: "Highlights from Digestive Disease Week: An Expert Interview with Lawrence R. Schiller, MD." 

Fadgyas-Stanculete M., , 2014.  Journal of Molecular Psychiatry

Medline Plus: "Amitriptyline" and "Desipramine."

Reviewed by Minesh Khatri on March 25, 2018

NEXT QUESTION:

How does talk therapy treat depression and symptoms of irritable bowel syndrome?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.