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What are the treatments for antisperm antibodies?

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Not all experts agree that it makes sense to test for antisperm antibodies. Some say we don’t have enough evidence about the best way to help people who have the antibodies and who want to have babies.

For men, your doctor may give you medication to lower your body’s immune response. That could lead to fewer antibodies and raise the chances that your female partner could get pregnant.

For women, one treatment that’s shown to help your chances of getting pregnant is intrauterine insemination. That’s when your doctor puts the sperm directly in your uterus. This allows the sperm to avoid contact with antisperm antibodies in your cervical mucus.

From: What Are Antisperm Antibodies? WebMD Medical Reference

SOURCES:

University of Utah Health: “Evaluating Male Fertility.”

S. Adam Ramin, MD, Providence Saint John's Health Center, Santa Monica, CA; founder and medical director, Urology Cancer Specialists, Los Angeles.

UpToDate: “Causes of male infertility.”

Actas Urológicas Espaõlas : “Antisperm antibodies and fertility association.”

International Journal of Fertility : “Treatment of infertility caused by antisperm antibodies.”

Methods in Molecular Biology : “Methods for direct and indirect antisperm antibody testing.”

Reproductive Medicine and Biology : “Diagnosis and treatment of immunologically infertile males with antisperm antibodies.”

National Institute for Health and Care Excellence: “Fertility: Do Not Do Recommendation.”

Middle Eastern Fertility Society Journal : “Zinc sulfate treatment of secondary male infertility associated with positive serum and seminal plasma anti-sperm antibody test.”

American Pregnancy Association: “Intrauterine Insemination.”

International Journal of Gynecology & Obstetrics : “Intrauterine insemination as a treatment of infertility in women with antisperm antibodies.”

Reviewed by Kecia Gaither on January 30, 2018

SOURCES:

University of Utah Health: “Evaluating Male Fertility.”

S. Adam Ramin, MD, Providence Saint John's Health Center, Santa Monica, CA; founder and medical director, Urology Cancer Specialists, Los Angeles.

UpToDate: “Causes of male infertility.”

Actas Urológicas Espaõlas : “Antisperm antibodies and fertility association.”

International Journal of Fertility : “Treatment of infertility caused by antisperm antibodies.”

Methods in Molecular Biology : “Methods for direct and indirect antisperm antibody testing.”

Reproductive Medicine and Biology : “Diagnosis and treatment of immunologically infertile males with antisperm antibodies.”

National Institute for Health and Care Excellence: “Fertility: Do Not Do Recommendation.”

Middle Eastern Fertility Society Journal : “Zinc sulfate treatment of secondary male infertility associated with positive serum and seminal plasma anti-sperm antibody test.”

American Pregnancy Association: “Intrauterine Insemination.”

International Journal of Gynecology & Obstetrics : “Intrauterine insemination as a treatment of infertility in women with antisperm antibodies.”

Reviewed by Kecia Gaither on January 30, 2018

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