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What targeted therapies treat metastatic lung cancer?

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These treatments can be used alone or with chemotherapy to treat lung cancer:

  • Afatinib (Gilotrif), dacomitinib (Vizimpro  erlotinib (Tarceva), and gefitinib (Iressa) all target a lung cancer cell protein called EGFR. They work if you need treatment in addition to chemotherapy. ),
  • Bevacizumab (Avastin) and ramucirumab (Cyramza) are used with chemotherapy. They stop tumor growth by cutting off the “food” -- nutrients, blood supply, and oxygen -- needed for them to grow.
  • Alectinib (Alecensa), brigatinib (Alunbrig), ceritinib (Zykadia), and crizotinib (Xalkori) are used for cancers with a gene rearrangement called ALK.

SOURCES:

Cancer Support Community: “Frankly Speaking about Cancer: Treatments for Advanced and Metastatic Lung Cancer.”

National Comprehensive Cancer Network: “NCCN Guidelines for Patients: Lung Cancer/Non-Small Cell Lung Cancer.”

National Cancer Institute: “Biological Therapies for Cancer,” “Lung Cancer Precision Medicine Trials: Adapting to Progress,” “More Immunotherapy Options Approved for Lung Cancer,” “SEER Training Modules: “Combination Treatments,” “Targeted Cancer Therapies.”

Translational Lung Cancer Research : “Immunotherapy in Lung Cancer.”

Memorial Sloan Kettering Cancer Center: “Combination Immunotherapy Shows New Promise for Lung Cancer.”

Lungcancer.org: “Non-small Cell Lung Cancer Treatment.”

Cancer Immunology Research: “Immune Checkpoint Inhibitors: Making Immunotherapy a Reality for the Treatment of Lung Cancer.”

American Cancer Society: “Immunotherapy for non-small cell lung cancer,” “Targeted therapy drugs for non-small cell lung cancer.”

Lung Cancer Alliance: “Immunotherapy for Lung Cancer: A Guide for the Patient.”

FDA: “Atezolizumab (TECENTRIQ).”

Therapeutic Advances in Medical Oncology : “Checkpoint inhibitors in lung cancer: latest developments and clinical potential.”

Cancer Treatment Reviews : “The abscopal effect of local radiotherapy: using immunology to make a rare event clinically relevant.”

Cancer.net: “When the First Treatment Doesn’t Work.”

Reviewed by Laura J. Martin on August 21, 2019

SOURCES:

Cancer Support Community: “Frankly Speaking about Cancer: Treatments for Advanced and Metastatic Lung Cancer.”

National Comprehensive Cancer Network: “NCCN Guidelines for Patients: Lung Cancer/Non-Small Cell Lung Cancer.”

National Cancer Institute: “Biological Therapies for Cancer,” “Lung Cancer Precision Medicine Trials: Adapting to Progress,” “More Immunotherapy Options Approved for Lung Cancer,” “SEER Training Modules: “Combination Treatments,” “Targeted Cancer Therapies.”

Translational Lung Cancer Research : “Immunotherapy in Lung Cancer.”

Memorial Sloan Kettering Cancer Center: “Combination Immunotherapy Shows New Promise for Lung Cancer.”

Lungcancer.org: “Non-small Cell Lung Cancer Treatment.”

Cancer Immunology Research: “Immune Checkpoint Inhibitors: Making Immunotherapy a Reality for the Treatment of Lung Cancer.”

American Cancer Society: “Immunotherapy for non-small cell lung cancer,” “Targeted therapy drugs for non-small cell lung cancer.”

Lung Cancer Alliance: “Immunotherapy for Lung Cancer: A Guide for the Patient.”

FDA: “Atezolizumab (TECENTRIQ).”

Therapeutic Advances in Medical Oncology : “Checkpoint inhibitors in lung cancer: latest developments and clinical potential.”

Cancer Treatment Reviews : “The abscopal effect of local radiotherapy: using immunology to make a rare event clinically relevant.”

Cancer.net: “When the First Treatment Doesn’t Work.”

Reviewed by Laura J. Martin on August 21, 2019

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Are there approved immunotherapy drugs for metastatic lung cancer?

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