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What are causes of pulmonary arterial hypertension (PAH) in the arteries?

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In rare cases, the problem is with the arteries themselves. They become narrow and stiff, leaving little room for blood to pass through. Causes of this type of pulmonary arterial hypertension (PAH) include:

Sometimes, doctors can’t tell what causes PAH.

  • A defect in a gene
  • An illness that affects many parts of your body, like lupus, sickle cell disease, or scleroderma
  • A heart defect you were born with that changes the normal way blood flows through it
  • Some drugs and toxins, especially diet drugs like fenfluramine (the "Fen" part of Fen-Phen) and street drugs like cocaine or methamphetamines that tighten blood vessels
  • Infection with HIV or a parasite called schistosoma

From: What Is Pulmonary Arterial Hypertension? WebMD Medical Reference

SOURCES:

National Heart, Lung, and Blood Institute: “What is Pulmonary Hypertension?”

American Heart Association: “Pulmonary Hypertension.”

American Thoracic Society: “Pulmonary Arterial Hypertension.”

Pulmonary Hypertension Association.

Stringham, R.  August 2010. American Family Physician, 

NCBI Bookshelf: “Heritable Pulmonary Arterial Hypertension.”

National Organization for Rare Disorders: “Pulmonary Arterial Hypertension.”

Kingrey, J:  Fall 2014. Pathlight, 

Reviewed by Neha Pathak on January 02, 2019

SOURCES:

National Heart, Lung, and Blood Institute: “What is Pulmonary Hypertension?”

American Heart Association: “Pulmonary Hypertension.”

American Thoracic Society: “Pulmonary Arterial Hypertension.”

Pulmonary Hypertension Association.

Stringham, R.  August 2010. American Family Physician, 

NCBI Bookshelf: “Heritable Pulmonary Arterial Hypertension.”

National Organization for Rare Disorders: “Pulmonary Arterial Hypertension.”

Kingrey, J:  Fall 2014. Pathlight, 

Reviewed by Neha Pathak on January 02, 2019

NEXT QUESTION:

What can you do if you might have pulmonary arterial hypertension (PAH)?

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