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What causes pulmonary arterial hypertension (PAH)?

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Most people get pulmonary arterial hypertension (PAH) when another illness damages their heart or lungs. The most common problems that raise your pulmonary blood pressure are:

  • Heart problems: Conditions like mitral valve disease or long-term high blood pressure damage the left side of the heart to the point that it doesn’t work well. That makes blood back up in the blood vessels of the lungs.
  • Lung diseases: When there’s a problem in your lungs, your body tries to protect its oxygen supply. It keeps the blood away from damaged areas and forces it into healthy areas. It can happen if you have sleep apnea, chronic obstructive pulmonary disease (COPD), and diseases that scar the lungs, like emphysema.
  • Blood clots
  • Other diseases, including some blood disorders, thyroid disease and other metabolic disorders, and immune system disorders that affect many different parts of the body, like sarcoidosis and vasculitis

From: What Is Pulmonary Arterial Hypertension? WebMD Medical Reference

SOURCES:

National Heart, Lung, and Blood Institute: “What is Pulmonary Hypertension?”

American Heart Association: “Pulmonary Hypertension.”

American Thoracic Society: “Pulmonary Arterial Hypertension.”

Pulmonary Hypertension Association.

Stringham, R.  August 2010. American Family Physician, 

NCBI Bookshelf: “Heritable Pulmonary Arterial Hypertension.”

National Organization for Rare Disorders: “Pulmonary Arterial Hypertension.”

Kingrey, J:  Fall 2014. Pathlight, 

Reviewed by Neha Pathak on January 2, 2019

SOURCES:

National Heart, Lung, and Blood Institute: “What is Pulmonary Hypertension?”

American Heart Association: “Pulmonary Hypertension.”

American Thoracic Society: “Pulmonary Arterial Hypertension.”

Pulmonary Hypertension Association.

Stringham, R.  August 2010. American Family Physician, 

NCBI Bookshelf: “Heritable Pulmonary Arterial Hypertension.”

National Organization for Rare Disorders: “Pulmonary Arterial Hypertension.”

Kingrey, J:  Fall 2014. Pathlight, 

Reviewed by Neha Pathak on January 2, 2019

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What are causes of pulmonary arterial hypertension (PAH) in the arteries?

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