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What is the treatment for drug-resistant tuberculosis?

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If several types of medications don't do the job, you have what doctors call multidrug-resistant TB. You’ll need to take a combination of medications for 20 to 30 months. They include:

A rare and serious type of the disease is called extensively drug-resistant TB. This means that many of the common medications -- including isoniazid, rifampin, fluoroquinolones, and at least one of the antibiotics that are injected -- don't knock it out. Research shows that it can be cured around 30% to 50% of the time.

  • Antibiotics called fluoroquinolones
  • An injectable antibiotic, such as amikacin (Amikin), capreomycin (Capastat), and kanamycin
  • Newer antibiotic treatments, such as bedaquiline (Sirturo), ethionamide (Trecator), and para-amino salicylic acid. These are given in addition to other medications. The new drug Pretomanid is used in conjunction with bedaquiline and linezolid.Scientists are still studying these medicines.

SOURCES:

Brian W. Christman, MD, Vanderbilt University Medical Center.

CDC: “Questions and Answers About Tuberculosis” and “Tuberculosis.”

American Lung Association: “Learn About Tuberculosis.”

Mayo Clinic: “Tuberculosis.”

World Health Organization: “Tuberculosis.”

Minnesota Department of Health: “Home Respiratory Precautions for Patients with Potentially Infectious Tuberculosis.”

Reviewed by Nayana Ambardekar on September 18, 2019

SOURCES:

Brian W. Christman, MD, Vanderbilt University Medical Center.

CDC: “Questions and Answers About Tuberculosis” and “Tuberculosis.”

American Lung Association: “Learn About Tuberculosis.”

Mayo Clinic: “Tuberculosis.”

World Health Organization: “Tuberculosis.”

Minnesota Department of Health: “Home Respiratory Precautions for Patients with Potentially Infectious Tuberculosis.”

Reviewed by Nayana Ambardekar on September 18, 2019

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What are side effects for treatments of tuberculosis?

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