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What are the uses and limitations of a C-reactive protein test for lupus?

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C-reactive protein (CRP) is a protein in the body that can be a marker of inflammation. The test looks for inflammation, which could indicate active lupus. In some cases, the test could be used to monitor inflammation. Results of the test could indicate changes in disease activity or in response to treatment. Because there are many causes for an elevated result, including infection, the test is not diagnostic for lupus. Nor can it distinguish a lupus flare from an infection. Also, the level of CRP doesn't directly correlate with lupus disease activity. So it isn't necessarily useful for monitoring disease activity.

From: Lab Tests for Lupus WebMD Medical Reference

SOURCES:

Robert Wood Johnson University Hospital: "Systemic Lupus Erythematosus (Lupus)."

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "Lupus: A Patient Care Guide for Nurses and Other Health Professionals, 3rd Edition."

Lupus Foundation of America: "Lab Tests."

NYU School of Medicine: "Neonatal Lupus."

Lupus Alliance of America: "Laboratory Tests for Lupus."

Children's Hospital of Pittsburgh: "Diagnosing Arthritis and Other Rheumatic Diseases."

Sjogren's Syndrome Foundation.

Reviewed by Jennifer Robinson on October 23, 2017

SOURCES:

Robert Wood Johnson University Hospital: "Systemic Lupus Erythematosus (Lupus)."

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "Lupus: A Patient Care Guide for Nurses and Other Health Professionals, 3rd Edition."

Lupus Foundation of America: "Lab Tests."

NYU School of Medicine: "Neonatal Lupus."

Lupus Alliance of America: "Laboratory Tests for Lupus."

Children's Hospital of Pittsburgh: "Diagnosing Arthritis and Other Rheumatic Diseases."

Sjogren's Syndrome Foundation.

Reviewed by Jennifer Robinson on October 23, 2017

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What are the uses and limitations of a complement proteins test for lupus?

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