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What is lupus nephritis?

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Lupus nephritis is inflammation of the kidney that is caused by systemic lupus erythematous (SLE). Also called lupus, SLE is an autoimmune disease. With lupus, the body's immune system targets its own body tissues. Lupus nephritis happens when lupus involves the kidneys.

Up to 60% of lupus patients will develop lupus nephritis. When the kidneys are inflamed, they can't function normally and can leak protein. If not controlled, lupus nephritis can lead to kidney failure.

From: Lupus Nephritis WebMD Medical Reference

SOURCES:

Cedars-Sinai: "Lupus" and "Lupus Nephritis."

Hospital for Special Surgery: "Lupus and Kidney Disease: What You Should Know about Lupus Nephritis (Lupus Kidney Disease)."

Lupus Foundation of America: "Kidney Disease."

National Kidney and Urologic Diseases Information Clearinghouse: "Lupus Nephritis."

Reviewed by David Zelman on August 09, 2017

SOURCES:

Cedars-Sinai: "Lupus" and "Lupus Nephritis."

Hospital for Special Surgery: "Lupus and Kidney Disease: What You Should Know about Lupus Nephritis (Lupus Kidney Disease)."

Lupus Foundation of America: "Kidney Disease."

National Kidney and Urologic Diseases Information Clearinghouse: "Lupus Nephritis."

Reviewed by David Zelman on August 09, 2017

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What are the symptoms of lupus nephritis?

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