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What causes nodular melanomas?

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It’s a type of skin cancer. It’s a dangerous form of melanoma that grows quickly. One main cause of nodular melanomas is the UV light from the sun and tanning beds. Their rays can harm the skin’s DNA. Rarely, you can get them on parts of your body that aren’t exposed to the sun.

When the DNA in skin cells become damaged, new cells can grow out of control. This can lead to melanoma. Experts aren’t exactly sure what causes this DNA damage and how it brings on cancer. It’s probably due to a mix of your genes, lifestyle habits, and UV exposure.

Melanomas develop in the cells that give your skin its color. Most of the time, they spread slowly in your skin’s top layer. But in nodular melanoma, the cancer grows downward. It can get into tissues, bones, and lymph nodes within weeks or months. That’s when the cancer is harder to treat.

From: What Is Nodular Melanoma? WebMD Medical Reference

SOURCES:

Laura Korb Ferris, MD, PhD, associate professor of dermatology, University of Pittsburgh; director of clinical trials, University of Pittsburgh Department of Dermatology.

Skin Cancer Foundation: “Types of Melanoma.”

American Cancer Society: “What Is Melanoma Skin Cancer?”

Cleveland Clinic: “Melanoma.”

JAMA Dermatology : “The Contribution of Nodular Subtype to Melanoma Mortality in the United States, 1978 to 2007.”

JAMA Dermatology : “History, Clinical, and Dermoscopic Characteristics of Thin Nodular Melanoma.”

Journal of Medical Case Reports : “Nodular Melanoma Presenting With Rapid Progression and Widespread Metasases: A Case Report.”

American Cancer Society: “Treating Melanoma Skin Cancer.”

Reviewed by Stephanie S. Gardner on September 12, 2017

SOURCES:

Laura Korb Ferris, MD, PhD, associate professor of dermatology, University of Pittsburgh; director of clinical trials, University of Pittsburgh Department of Dermatology.

Skin Cancer Foundation: “Types of Melanoma.”

American Cancer Society: “What Is Melanoma Skin Cancer?”

Cleveland Clinic: “Melanoma.”

JAMA Dermatology : “The Contribution of Nodular Subtype to Melanoma Mortality in the United States, 1978 to 2007.”

JAMA Dermatology : “History, Clinical, and Dermoscopic Characteristics of Thin Nodular Melanoma.”

Journal of Medical Case Reports : “Nodular Melanoma Presenting With Rapid Progression and Widespread Metasases: A Case Report.”

American Cancer Society: “Treating Melanoma Skin Cancer.”

Reviewed by Stephanie S. Gardner on September 12, 2017

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Who gets nodular melanomas?

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