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What are 5-alpha reductase inhibitors (5-ARIs) and how ido they treat benign prostatic hyperplasia (BPH)?

ANSWER

These drugs are prescribed for BPH, also called enlarged prostate. They block hormones in your body that make your prostate grow. They can even shrink it. 5-ARIs seem to work best for men with very large prostates.

These drugs can make it easier to pee. They also may help prevent bladder damage or other problems, and lower the chances that you’ll need surgery.

It can take up to 6 months to see the full effects of 5-ARIs, and you have to keep taking them to get results.

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil).

Reviewed by Carmelita Swiner on November 18, 2020

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil).

Reviewed by Carmelita Swiner on November 18, 2020

NEXT QUESTION:

What are the side effects of 5-alpha reductase inhibitors (5-ARIs) used to treat benign prostatic hyperplasia (BPH)?

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