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What are phosphodiesterase-5 inhibitors and how do they help treat benign prostatic hyperplasia (BPH)?

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These are drugs that treat BPH, also called enlarged prostate. These are the same medicines used to treat erectile dysfunction. They smooth muscles in the bladder and prostate, which can help ease BPH symptoms

The FDA has approved only one phosphodiesterase-5 inhibitor for BPH: Tadalafil (Cialis). This drug is used less often as some others to treat enlarged prostate. But it can be an option if you also have problems getting or keeping an erection.

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil).

Reviewed by Carmelita Swiner on November 18, 2020

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil).

Reviewed by Carmelita Swiner on November 18, 2020

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What are the side effects of using tadalafil (Cialis) for benign prostatic hyperplasia (BPH)?

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