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What are the two main 5-alpha reductase inhibitors (5-ARIs) for benign prostatic hyperplasia (BPH)?

ANSWER

5-alpha reductase inhibitors are drugs that treat benign prostatic hyperplasia, also called enlarged prostate. There are two main types:

  • Finasteride (Propecia, Proscar)
  • Dutasteride (Avodart)

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil) ” .

Reviewed by Laura J. Martin on November 18, 2018

SOURCES:

PubMed: “Various treatment options for benign prostatic hyperplasia: A current update.”

Mayo Clinic: “Benign Prostatic Hyperplasia (BPH).”

Johns Hopkins: “Benign Prostatic Hyperplasia.”

Urology Care Foundation: “Benign Prostatic Hyperplasia (BPH).”

Merck, “Highlights of Prescribing Information: Propecia.”

American Academy of Ophthalmology: “Alpha-Blocker Patient Advisory ASCRS and AAO Information Statement.”

NHS: “Treating Benign Prostate Enlargement.”

NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: “Prostate Enlargement: Benign Prostatic Hyperplasia.”

Medscape: “Benign Prostatic Hypertrophy Treatment & Management.”

FDA: “Questions and Answers for Cialis (tadalafil) ” .

Reviewed by Laura J. Martin on November 18, 2018

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What are phosphodiesterase-5 inhibitors and how do they help treat benign prostatic hyperplasia (BPH)?

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