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What are the pros to using estrogen replacement therapy vaginal suppositories, rings, and creams?

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For treating the vaginal symptoms of menopause (like dryness), these treatments are more effective than other forms of estrogen therapy. Like patches, some of these treatments might be more convenient than taking a daily pill. Some vaginal suppositories and rings are low-dose, and only affect the immediate area. The advantage is that they can relieve vaginal symptoms without exposing your whole body to high doses of estrogen. While the theory is that this may lower the more serious risks of estrogen therapy, that's not certain. And it won't help with other symptoms, like hot flashes.

SOURCES:

ACP Medicine web site: "Menopause."

Canonico M et al, Circulation, Feb. 20, 2007; vol 115: pp 840-845.

MedicineNet web site: "Hormone Creams: Safe and Effective?"

National Cancer Institute web site: "How to Deal with Surgical Menopause."

National Institutes of Health web site: "Facts About Menopausal Hormone Therapy."

National Institutes of Health Medline Plus web site: "Estrogen," "Estrogen Vaginal," "Estradiol Topical," "Estradiol Transdermal."

  Practice Committee of the American Society for Reproductive Medicine, Fertility and Sterility, November 2006; vol 86: pp S75-S88.

National Women's Health information Center: "Menopause and Menopause Treatments." WebMD Medical Reference: "Estrogen Replacement Therapy," "Low Dose Estrogen for Dryness and Atrophy."

Reviewed by Nivin Todd on October 31, 2019

SOURCES:

ACP Medicine web site: "Menopause."

Canonico M et al, Circulation, Feb. 20, 2007; vol 115: pp 840-845.

MedicineNet web site: "Hormone Creams: Safe and Effective?"

National Cancer Institute web site: "How to Deal with Surgical Menopause."

National Institutes of Health web site: "Facts About Menopausal Hormone Therapy."

National Institutes of Health Medline Plus web site: "Estrogen," "Estrogen Vaginal," "Estradiol Topical," "Estradiol Transdermal."

  Practice Committee of the American Society for Reproductive Medicine, Fertility and Sterility, November 2006; vol 86: pp S75-S88.

National Women's Health information Center: "Menopause and Menopause Treatments." WebMD Medical Reference: "Estrogen Replacement Therapy," "Low Dose Estrogen for Dryness and Atrophy."

Reviewed by Nivin Todd on October 31, 2019

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What are the cons to using estrogen replacement therapy vaginal suppositories, rings, and creams?

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