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Can naltrexone help treat opioid use disorder?

ANSWER

Naltrexone can help treat opioid use disorder. It blocks opiate receptors. Unlike methadone, another drug used to treat opioid use disorder, it can’t ease withdrawal symptoms or cravings. But you can’t get high if you use drugs while taking it. Naltrexone works best as part of a broad recovery treatment program. You’ll start it when you’re done with detox.

SOURCES:

Carroll K.M.   2005. American Journal of Psychiatry,

FDA. "FDA approves first buprenorphine implant for treatment of opioid dependence."

Kosten, T.R. 2003. New England Journal of Medicine,

Mattick, R.P. 2003. Cochrane Database of Systematic Reviews,

Medline Plus: "Opiate withdrawal."

Moore & Jefferson, 2nd edition, Mosby 2004. Handbook of Medical Psychiatry,

Narcotics Anonymous web site.

National Library of Medicine web site.

Van den Brink, W. 2006. Canadian Journal of Psychiatry,

National Institutes of Health: “How Do Opioids Work?”

Journal of Addiction Research & Therapy : “Addiction Relapse and Its Predictors: A Prospective Study.”

SAMHSA: “Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction.”

PubMed Health: “Buprenorphine,” “Naloxone."

National Institute on Drug Abuse: “How Do Medications to Treat Opioid Addiction Work?”

Medscape: “Opioid Abuse Treatment & Management.”

Reviewed by Melinda Ratini on August 19, 2018

SOURCES:

Carroll K.M.   2005. American Journal of Psychiatry,

FDA. "FDA approves first buprenorphine implant for treatment of opioid dependence."

Kosten, T.R. 2003. New England Journal of Medicine,

Mattick, R.P. 2003. Cochrane Database of Systematic Reviews,

Medline Plus: "Opiate withdrawal."

Moore & Jefferson, 2nd edition, Mosby 2004. Handbook of Medical Psychiatry,

Narcotics Anonymous web site.

National Library of Medicine web site.

Van den Brink, W. 2006. Canadian Journal of Psychiatry,

National Institutes of Health: “How Do Opioids Work?”

Journal of Addiction Research & Therapy : “Addiction Relapse and Its Predictors: A Prospective Study.”

SAMHSA: “Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction.”

PubMed Health: “Buprenorphine,” “Naloxone."

National Institute on Drug Abuse: “How Do Medications to Treat Opioid Addiction Work?”

Medscape: “Opioid Abuse Treatment & Management.”

Reviewed by Melinda Ratini on August 19, 2018

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What do I need to know about counseling for opioid addiction?

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