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Which medications will your doctor try first for the treatment of posttraumatic stress disorder (PTSD)?

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Several types of drugs affect the chemistry in your brain related to fear and anxiety. Medications probably won't get rid of your PTSD symptoms, but they can make them less intense and more manageable.

Doctors will usually start with ones that affect the neurotransmitters serotonin or norepinephrine (SSRIs and SNRIs), including:

The FDA has approved only paroxetine and sertraline for treating PTSD.

  • Fluoxetine (Prozac)
  • Paroxetine (Paxil)
  • Sertraline (Zoloft)
  • Venlafaxine (Effexor)

From: What Are the Treatments for PTSD? WebMD Medical Reference

SOURCES:

Mayo Clinic: "Post-traumatic Stress Disorder."

Cleveland Clinic: "Anxiety Disorders."

U.S. Department of Veterans Affairs: "Treatment of PTSD," "Clinician's Guide to Medications for PTSD," "Medications for PTSD."

UpToDate: "Pharmacotherapy for posttraumatic stress disorder in adults."

Society of Clinical Psychology: "Stress Inoculation Training for Post-Traumatic Stress Disorder."

Medscape: "Posttraumatic Stress Disorder Medication."

Reviewed by Smitha Bhandari on November 07, 2017

SOURCES:

Mayo Clinic: "Post-traumatic Stress Disorder."

Cleveland Clinic: "Anxiety Disorders."

U.S. Department of Veterans Affairs: "Treatment of PTSD," "Clinician's Guide to Medications for PTSD," "Medications for PTSD."

UpToDate: "Pharmacotherapy for posttraumatic stress disorder in adults."

Society of Clinical Psychology: "Stress Inoculation Training for Post-Traumatic Stress Disorder."

Medscape: "Posttraumatic Stress Disorder Medication."

Reviewed by Smitha Bhandari on November 07, 2017

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What "off label" medications might your doctor prescribe for posttraumatic stress disorder (PTSD)?

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