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Are tricyclic antidepressants used to treat migraines?

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Tricyclic antidepressants used to treat migraines include amitriptyline and nortriptyline (Aventyl,Pamelor). Research suggests duloxetine (Cymbalta) and venlafaxine (Effexor XR) may be helpful in preventing migraines.

SOURCES:  American Academy of Neurology: "Evidence-Based Guidelines for Migraine Headache."  George R. Nissan, DO, director of research, Diamond Headache Clinic, Chicago. News release, FDA.





Reviewed by Melinda Ratini on May 28, 2018

SOURCES:  American Academy of Neurology: "Evidence-Based Guidelines for Migraine Headache."  George R. Nissan, DO, director of research, Diamond Headache Clinic, Chicago. News release, FDA.





Reviewed by Melinda Ratini on May 28, 2018

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When can preventive migraine medication not be right for me?

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