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How are ergots used to treat migraines?

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Drugs that combine ergotamine and caffeine (Cafergot, Migergot) may be an option if your headaches come often and the pain lasts more than two days at a time. But they don't work as well as triptans. They also can cause nausea and rebound headaches. Dihydroergotamine (D.H.E. 45, Migranal) is another option. It's similar to ergotamine but more effective. You can take it as a nasal spray or shot.

SOURCES:

American Heart Association: "Types of Blood Pressure Medications."

American Migraine Foundation: "Commonly Used Acute Migraine Treatments."

Mayo Clinic: "Mayo Clinic Q and A: Botox a Treatment for Chronic Migraines, But Not a Cure" and "Migraine Treatment."

National Institute of Neurological Disorders and Stroke: "NINDS Migraine Information Page."

Neurology : "Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults."

The Migraine Trust: "Medication."

UpToDate: "Patient education: Migraine headaches in adults (Beyond the Basics)."

Reviewed by Neil Lava on June 10, 2017

SOURCES:

American Heart Association: "Types of Blood Pressure Medications."

American Migraine Foundation: "Commonly Used Acute Migraine Treatments."

Mayo Clinic: "Mayo Clinic Q and A: Botox a Treatment for Chronic Migraines, But Not a Cure" and "Migraine Treatment."

National Institute of Neurological Disorders and Stroke: "NINDS Migraine Information Page."

Neurology : "Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults."

The Migraine Trust: "Medication."

UpToDate: "Patient education: Migraine headaches in adults (Beyond the Basics)."

Reviewed by Neil Lava on June 10, 2017

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