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How can calcitonin gene-related peptide (CGRP) inhibitors help in treating migraine?

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CGRP (calcitonin gene-related peptide) is a molecule involved in causing migraine pain. CGRP inhibitors are a new class of drugs that block the effects of CGRP. Erenumab (Aimovig) is the first medicine specifically approved to prevent migraine attacks. You give yourself an injection once a month with a pen-like device.

SOURCES: FDA: “Treating migraines: more ways to fight the pain.” News releases, FDA. American Headache Society: “Botox-A for suppression of chronic migraine: frequently asked questions.” American Migraine Foundation: “Sphenopalatine ganglion blocks for headache disorders.” Medscape.com: “Image-guided lidocaine injections for headache.” National Headache Foundation: “New procedure may bring migraine relief.” Smitherman, T. published online March 29, 2015. Association for Contextual Behavioral Science: “A Short Guide to Acceptance and Commitment Therapy.” American Headache Society: “Mindfulness meditation for migraine.” Bromberg, J. 2012.









Current Pain Headache Reports,Headache,

Reviewed by Melinda Ratini on May 23, 2018

SOURCES: FDA: “Treating migraines: more ways to fight the pain.” News releases, FDA. American Headache Society: “Botox-A for suppression of chronic migraine: frequently asked questions.” American Migraine Foundation: “Sphenopalatine ganglion blocks for headache disorders.” Medscape.com: “Image-guided lidocaine injections for headache.” National Headache Foundation: “New procedure may bring migraine relief.” Smitherman, T. published online March 29, 2015. Association for Contextual Behavioral Science: “A Short Guide to Acceptance and Commitment Therapy.” American Headache Society: “Mindfulness meditation for migraine.” Bromberg, J. 2012.









Current Pain Headache Reports,Headache,

Reviewed by Melinda Ratini on May 23, 2018

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