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What medicines can help with menopausal migraines?

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Migraine drugs fall into two categories. Medicines that help prevent migraines from starting:

Medicines that relieve a migraine once it has already started:

  • Antidepressants: venlafaxine (Effexor), amitriptyline (Elavil)
  • Anti-seizure drugs: divalproex sodium (Depakote), topiramate (Topamax), valproate sodium (Depacon), valproic acid (Depakene and Stavzor)
  • Blood pressure medicines: beta blockers, calcium-channel blockers
  • CGRP inhibitors: Erenumab (Aimovig) and fremanezumab (Ajovy) block the effect of calcitonin gene-related peptide molecules
  • Pain relievers: acetaminophen (Panadol, Tylenol), aspirin, ibuprofen (Advil, Motrin,), naproxen (Aleve)
  • Triptans: eletriptan (Relpax), frovatriptan (Frova), rizatriptan (Maxalt), sumatriptan (Alsuma, Imitrex, Treximet), zolmitriptan (Zomig)

From: Migraines and Menopause WebMD Medical Reference

SOURCES:

American Migraine Foundation: "About Migraine."

Cleveland Clinic: "Hormone Headaches/Menstrual Migraines."

MedlinePlus: “Acetaminophen,” "Valporic Acid.”

MacGregor, E. , January 2009. Current Treatment Options in Neurology

Nappi, R. , June 2009. Menopause International

National Institute of Neurological Disorders and Stroke: "NINDS Migraine Information Page."

The North American Menopause Society: "My-Oh-Migraine: Hormonal Headaches and Menopause."

The Migraine Trust: "Menopause, Midlife and Migraine."

University of California, Berkeley Health Services: "Migraine Triggers."

Reviewed by Melinda Ratini on May 22, 2018

SOURCES:

American Migraine Foundation: "About Migraine."

Cleveland Clinic: "Hormone Headaches/Menstrual Migraines."

MedlinePlus: “Acetaminophen,” "Valporic Acid.”

MacGregor, E. , January 2009. Current Treatment Options in Neurology

Nappi, R. , June 2009. Menopause International

National Institute of Neurological Disorders and Stroke: "NINDS Migraine Information Page."

The North American Menopause Society: "My-Oh-Migraine: Hormonal Headaches and Menopause."

The Migraine Trust: "Menopause, Midlife and Migraine."

University of California, Berkeley Health Services: "Migraine Triggers."

Reviewed by Melinda Ratini on May 22, 2018

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What can help to prevent menopausal migraines?

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