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How do glucocorticoids work?

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If you have an autoimmune disease, your body triggers inflammation by mistake. That means your immune system attacks healthy cells and tissue as if they were viruses or bacteria.

Glucocorticoids keep your body from pumping out so many of the chemicals involved in inflammation. They can also dial back your immune system’s response by changing the way white blood cells work.

From: What Are Glucocorticoids? WebMD Medical Reference

SOURCES:

Huntington’s Outreach Project for Education, at Stanford: “Glucocorticoids.”

Mayo Clinic: “Corticosteroid,” “Cortisone shots,” “Dexamethasone,” “Triamcinolone,” “Budesonide.”

National Institutes of Health: “Understanding Autoimmune Diseases.”

Molecular and Cellular Endocrinology : “The anti-inflammatory and immunosuppressive effect of glucocorticoids, recent developments and mechanistic insights.”

National Health Service: “Steroids.”

Cleveland Clinic: “Corticosteroids.”

Medscape: “Immunology of Transplant Rejection.”

Reviewed by Jennifer Robinson on May 30, 2019

SOURCES:

Huntington’s Outreach Project for Education, at Stanford: “Glucocorticoids.”

Mayo Clinic: “Corticosteroid,” “Cortisone shots,” “Dexamethasone,” “Triamcinolone,” “Budesonide.”

National Institutes of Health: “Understanding Autoimmune Diseases.”

Molecular and Cellular Endocrinology : “The anti-inflammatory and immunosuppressive effect of glucocorticoids, recent developments and mechanistic insights.”

National Health Service: “Steroids.”

Cleveland Clinic: “Corticosteroids.”

Medscape: “Immunology of Transplant Rejection.”

Reviewed by Jennifer Robinson on May 30, 2019

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What inflammatory conditions can glucocorticoids treat?

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