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What are recent findings and ongoing research on the root causes of MS?

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Besides testing new treatments, scientists continue to explore the root causes of MS. Much of the research is still being done in animals, but recent findings and ongoing research include:

  • Bone marrow stem cell transplants that would offer long-term benefits
  • An epilepsy pill that slowed nerve damage
  • A specific type of training that improved memory and brain activity (as seen on MRI scans). Changes were still in place after 6 months.
  • An experimental therapy in mice helped their bodies make myelin, a substance that protects nerves. The treatment is a type of microRNA, a small amount of genetic material.
  • A large team of researchers is analyzing gut bacteria to find out what role it may play as MS gets worse.
  • Researchers are studying children with MS to learn how their environment and genes make them more likely to get the disease. One early finding suggested low vitamin D levels were linked to MS relapses in kids with a specific gene.

From: Multiple Sclerosis Research Roundup WebMD Medical Reference

National Multiple Sclerosis Society: “Bone Marrow Stem Cell Transplant -- HSCT,” “Ending the Disease Forever,” “Multiple Sclerosis FAQs,” “News Release,” “Restoring What’s Been Lost,” “Searching for MS Genes,” “Stopping MS in its Tracks.”

Mayo Clinic: “Bone Marrow Transplant: Overview,” “Bone Marrow Transplant: Why it’s done.”

National Institutes of Health: “Nanotechnology at NIH.”

Advanced Pharmaceutical Bulletin : “Nanomedicine in Central Nervous System (CNS) Disorders: A Present and Future Prospective.”

ACS Nano : “Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain.”

PNAS : “In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.”

Journal of Immunotoxicology : “Application of nanomedicine for crossing the blood-brain barrier: Theranostic opportunities in multiple sclerosis.”

Reviewed by Neil Lava on May 05, 2019

National Multiple Sclerosis Society: “Bone Marrow Stem Cell Transplant -- HSCT,” “Ending the Disease Forever,” “Multiple Sclerosis FAQs,” “News Release,” “Restoring What’s Been Lost,” “Searching for MS Genes,” “Stopping MS in its Tracks.”

Mayo Clinic: “Bone Marrow Transplant: Overview,” “Bone Marrow Transplant: Why it’s done.”

National Institutes of Health: “Nanotechnology at NIH.”

Advanced Pharmaceutical Bulletin : “Nanomedicine in Central Nervous System (CNS) Disorders: A Present and Future Prospective.”

ACS Nano : “Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain.”

PNAS : “In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.”

Journal of Immunotoxicology : “Application of nanomedicine for crossing the blood-brain barrier: Theranostic opportunities in multiple sclerosis.”

Reviewed by Neil Lava on May 05, 2019

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