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What causes clinically isolated syndrome (CIS)?

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When you have CIS, your body attacks and damages the protective coating around your nerves, called myelin. That keeps your nerves from sending signals the way they should. It's what causes your symptoms.

Doctors aren't sure why the body attacks itself this way. Some think a virus could be to blame, but the exact cause of CIS is unknown.

SOURCES:

National Multiple Sclerosis Society: “What is MS? Related conditions: Clinically isolated syndrome (CIS).” National Multiple Sclerosis Society: “Symptoms & diagnosis: MS symptoms.”

National Institute of Neurological Disorders and Stroke: “NINDS multiple sclerosis information page.” National Multiple Sclerosis Society: “Symptoms & diagnosis: Clinically isolated syndrome (CIS).”

Kuhle J et.al. Multiple Sclerosis Journal, February 2015.

National Multiple Sclerosis Society: “Treating MS: Medications: Adherence.”

National Multiple Sclerosis Society: “Symptoms & diagnosis: Possible MS.”

Multiple Sclerosis Trust: “Clinically isolated syndrome (CIS).”

Reviewed by Christopher Melinosky on November 14, 2019

SOURCES:

National Multiple Sclerosis Society: “What is MS? Related conditions: Clinically isolated syndrome (CIS).” National Multiple Sclerosis Society: “Symptoms & diagnosis: MS symptoms.”

National Institute of Neurological Disorders and Stroke: “NINDS multiple sclerosis information page.” National Multiple Sclerosis Society: “Symptoms & diagnosis: Clinically isolated syndrome (CIS).”

Kuhle J et.al. Multiple Sclerosis Journal, February 2015.

National Multiple Sclerosis Society: “Treating MS: Medications: Adherence.”

National Multiple Sclerosis Society: “Symptoms & diagnosis: Possible MS.”

Multiple Sclerosis Trust: “Clinically isolated syndrome (CIS).”

Reviewed by Christopher Melinosky on November 14, 2019

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Who is at a high risk of developing clinically isolated syndrome?

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