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What causes multiple sclerosis flare-ups?

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Flare-ups happen when inflammation in your nervous system damages the layer that covers and protects nerve cells. This slows or stops nerve cell signals from getting to the parts of your body where they need to go.

If you have relapsing-remitting multiple sclerosis, you may have flare-ups followed by symptom-free periods called remissions. To be a true relapse, the symptoms must start at least 30 days after your last flare-up and should stick around for at least 24 hours.

Cleveland Clinic: "Avoid 8 Common Triggers to Make Your Life with MS Easier."

Multiple Sclerosis Association of America: "Acthar Gel."

Multiple Sclerosis Society (UK): "Managing Relapses," "Relapsing Remitting (RRMS)."

National Multiple Sclerosis Society: "Managing Relapses."

Ontaneda, D.  , October-December 2009. Annals of Indian Academy of Neurology

Paturel, A.  , January/February 2009. Neurology Now

Reviewed by Neil Lava on May 5, 2019

Cleveland Clinic: "Avoid 8 Common Triggers to Make Your Life with MS Easier."

Multiple Sclerosis Association of America: "Acthar Gel."

Multiple Sclerosis Society (UK): "Managing Relapses," "Relapsing Remitting (RRMS)."

National Multiple Sclerosis Society: "Managing Relapses."

Ontaneda, D.  , October-December 2009. Annals of Indian Academy of Neurology

Paturel, A.  , January/February 2009. Neurology Now

Reviewed by Neil Lava on May 5, 2019

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What happens during a multiple sclerosis flare-up?

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