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What disease-modifying drugs are used to reduce flare-ups in multiple sclerosis?

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Disease-modifying drugs that can reduce the number of flare-ups include:

Medicines that both cut down the number of flare-ups and slow the advance of MS include:

  • Glatiramer acetate (Copaxone, Glatopa)
  • Interferon beta-1b (Betaseron, Extavia)
  • Daclizumab (Zinbryta)
  • Dimethyl fumarate (Tecfidera)
  • Fingolimod (Gilenya)
  • Interferon beta-1a (Avonex, Rebif)
  • Mitoxantrone (Novantrone)
  • Natalizumab (Tysabri)
  • Ocrelizumab (Ocrevus)
  • Peginterferon beta-1a (Plegridy)
  • Teriflunomide (Aubagio)

From: Treatments for Multiple Sclerosis WebMD Medical Reference

National Multiple Sclerosis Society: "Disease Management Consensus Statement," "Fingolimod," "Novantrone (mitoxantrone),"  "Exacerbations,"  "FDA Approves Plegridy (Pegylated Interferon Beta) For Relapsing MS."

John Ratchford, MD, assistant professor of neurology, Johns Hopkins School of Medicine.

NINDS: "Multiple Sclerosis Information Page."

Goldman, L.  , Saunders Elsevier, 2007. Cecil Medicine

FDA: "Safety Update on Progressive Multifocal Leukoencephalopathy (PML) Associated with Tysabri," "FDA approves new multiple sclerosis treatment Aubagio," "FDA investigating rare brain infection in patient taking Gilenya (fingolimod)."

Reviewed by Neil Lava on March 13, 2018

National Multiple Sclerosis Society: "Disease Management Consensus Statement," "Fingolimod," "Novantrone (mitoxantrone),"  "Exacerbations,"  "FDA Approves Plegridy (Pegylated Interferon Beta) For Relapsing MS."

John Ratchford, MD, assistant professor of neurology, Johns Hopkins School of Medicine.

NINDS: "Multiple Sclerosis Information Page."

Goldman, L.  , Saunders Elsevier, 2007. Cecil Medicine

FDA: "Safety Update on Progressive Multifocal Leukoencephalopathy (PML) Associated with Tysabri," "FDA approves new multiple sclerosis treatment Aubagio," "FDA investigating rare brain infection in patient taking Gilenya (fingolimod)."

Reviewed by Neil Lava on March 13, 2018

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