The most common symptom of osteoarthritis is pain in the affected joints after repetitive use. Joint pain is usually worse later in the day. There can be swelling, warmth, and creaking of the affected joints. Pain and stiffness of the joints can also occur after long periods of inactivity, for example, sitting in a theater. In severe osteoarthritis, complete loss of cartilage causes friction between bones, causing pain at rest or pain with limited motion.
Osteoarthritis Health Center
FDA OKs Powerful New Opioid Dsuvia Despite Criticisms
An FDA advisory committee did recommend for approval of Dsuvia in a 10-3 vote last month. But the committee's chair took the highly unusual move of voicing his opposition at that time. Dr. Raeford Brown, a professor of anesthesiology and pediatrics at the University of Kentucky, urged the FDA to reject the drug.
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