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What are side effects of hyaluronic acid injections for osteoarthritis?

ANSWER

The most common short-term side effects are minor pain at the injection site and minor buildup of joint fluid. These get better within a few days.

Infrequently the injected joint may flare up with more inflammation.

SOURCES:

American Academy of Family Physicians: ''Intra-articular Hyaluronic Acid Injections for Knee Osteoarthritis.''

American Academy of Orthopedic Surgeons: "Viscosupplementation Therapy for Arthritis."

Arthritis Foundation: "Study Questions Effectiveness of Viscosupplementation."

Bellamy. , April 19, 2006. Cochrane Database Systematic Reviews

Das, A; Neher, JO; and Safrenek, 2009. Journal of Family Practice,

Medscape: "VIscosupplementation in Knee OA May Not Be Worth the Risk."

Rutjes. , Aug. 7, 2012. Annals of Internal Medicine

Reviewed by David Zelman on April 22, 2019

SOURCES:

American Academy of Family Physicians: ''Intra-articular Hyaluronic Acid Injections for Knee Osteoarthritis.''

American Academy of Orthopedic Surgeons: "Viscosupplementation Therapy for Arthritis."

Arthritis Foundation: "Study Questions Effectiveness of Viscosupplementation."

Bellamy. , April 19, 2006. Cochrane Database Systematic Reviews

Das, A; Neher, JO; and Safrenek, 2009. Journal of Family Practice,

Medscape: "VIscosupplementation in Knee OA May Not Be Worth the Risk."

Rutjes. , Aug. 7, 2012. Annals of Internal Medicine

Reviewed by David Zelman on April 22, 2019

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What are side effects of hyaluronic acid for osteoarthritis?

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