PREVIOUS QUESTION:

 

NEXT QUESTION:

 

What does the presence of HLA-B27 indicate in relation to rheumatoid arthritis?

ANSWER

HLA-B27 is a genetic marker. In people with inflammatory arthritis of the spine and joints (not osteoarthritis), a positive HLA-B27 test is associated with the presence of one of a group of diseases called seronegative spondyloarthropathies. This includes diseases such as ankylosing spondylitis (AS), psoriatic arthritis, and Reiter's syndrome (also called reactive arthritis). HLA-B27 is present in about 90% of people with AS, but the gene can also be seen in people with no sign of arthritis or inflammation.

SOURCES: American Association for Clinical Chemistry: "Rheumatoid Factor." National Institute of Arthritis and Musculoskeletal and Skin Diseases: "How is Rheumatoid Arthritis Diagnosed?" Arthritis Foundation: "Guide to Lab Tests."


Reviewed by Brunilda Nazario on April 09, 2018

SOURCES: American Association for Clinical Chemistry: "Rheumatoid Factor." National Institute of Arthritis and Musculoskeletal and Skin Diseases: "How is Rheumatoid Arthritis Diagnosed?" Arthritis Foundation: "Guide to Lab Tests."


Reviewed by Brunilda Nazario on April 09, 2018

NEXT QUESTION:

What does it mean if muscle enzymes are too high in relation to rheumatoid arthritis?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.