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What causes Paget's disease?

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Doctors don't really know what causes Paget's disease. It may be a viral infection of the bone, or it could be caused by something in the environment. In about 15% to 30% of cases, there's a family history of Paget's. Researchers have found a few genes that can make it more likely that you or a family member will get it. Smoking may also increase your chances.

If you have family members with it, you should get a blood test every 2 to 3 years after age 40.

From: What Is Paget's Disease of Bone? WebMD Medical Reference

SOURCES:

American Academy of Orthopedic Surgeons: "Paget's Disease of Bone."

American College of Rheumatology: "Paget's Disease of Bone."

Mayo Clinic: "Paget's disease of bone."

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "What Is Paget's Disease of Bone? Fast Facts."

NIHSeniorHealth: "Paget's Disease of Bone."

National Organization for Rare Diseases: "Paget's Disease."

Mount Sinai Hospital: "Paget's Disease."

Reviewed by Sabrina Felson on October 28, 2018

SOURCES:

American Academy of Orthopedic Surgeons: "Paget's Disease of Bone."

American College of Rheumatology: "Paget's Disease of Bone."

Mayo Clinic: "Paget's disease of bone."

National Institute of Arthritis and Musculoskeletal and Skin Diseases: "What Is Paget's Disease of Bone? Fast Facts."

NIHSeniorHealth: "Paget's Disease of Bone."

National Organization for Rare Diseases: "Paget's Disease."

Mount Sinai Hospital: "Paget's Disease."

Reviewed by Sabrina Felson on October 28, 2018

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What are symptoms of Paget's disease?

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