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What drugs might you take with levodopa for Parkinson's disease?

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Carbidopa makes the levodopa work better, so you can take less of it. It's one of the drugs in Sinemet. Your doctor may also want you to take dopamine agonist like pramipexole (Mirapex), ropinirole (Requip), or rotigotine (Neupro).

Safinamide (Xadago) is an add-on medicine that your doctor may prescribe when you're taking levdopoa and carbidopa and have a breakthrough of symptoms that used to be under control.

When you take levodopa, a chemical in your body called COMT makes part of the drug useless. Entacapone (Comtan) and tolcapone (Tasmar) block COMT, so the brain can use levodopa more effectively.

From: Medications for Parkinson's Disease WebMD Medical Reference

Reviewed by Neil Lava on January 20, 2019

Medically Reviewed on 1/20/2019

SOURCES:

FDA. "FDA approves drug to treat Parkinson’s disease."

National Parkinson Foundation: "How Is PD Treated?" “Carbidopa-Levodopa,” “Dopamine agonists,” “MAO-B inhibitors.”

Parkinson's Disease Foundation: "Medications & Treatments."

UpToDate: "Patient information: Parkinson disease treatment options -- medications (Beyond the Basics)."

Teva Neuroscience Inc.

 

Reviewed by Neil Lava on January 20, 2019

SOURCES:

FDA. "FDA approves drug to treat Parkinson’s disease."

National Parkinson Foundation: "How Is PD Treated?" “Carbidopa-Levodopa,” “Dopamine agonists,” “MAO-B inhibitors.”

Parkinson's Disease Foundation: "Medications & Treatments."

UpToDate: "Patient information: Parkinson disease treatment options -- medications (Beyond the Basics)."

Teva Neuroscience Inc.

 

Reviewed by Neil Lava on January 20, 2019

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