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Why do doctors try to delay starting people on levodopa for Parkinson's disease?

ANSWER

Most doctors try to delay starting people on levodopa as long as possible because the drug tends to stop working as well after a while. Sometimes, if you've been taking levodopa for several years, the medicine's effects can wear off and you develop movement problems called "motor fluctuations." These problems can happen gradually or suddenly.

SOURCES: 

Journal of the American Medical Association

American Academy of Family Physicians. 

National Parkinson Foundation. 

American Parkinson Disease Foundation. 

Parkinson's UK: "Wearing Off and Dyskinesia."

Teva Pharmaceuticals Inc.

FDA. "FDA approves drug to treat Parkinson’s disease."  

Reviewed by Neil Lava on January 20, 2019

SOURCES: 

Journal of the American Medical Association

American Academy of Family Physicians. 

National Parkinson Foundation. 

American Parkinson Disease Foundation. 

Parkinson's UK: "Wearing Off and Dyskinesia."

Teva Pharmaceuticals Inc.

FDA. "FDA approves drug to treat Parkinson’s disease."  

Reviewed by Neil Lava on January 20, 2019

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How can dopamine agonists help with treating Parkinson's disease?

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