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How do anti-androgen drugs treat advanced prostate cancer?

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Sometimes, GnRH agents cause your body to temporarily make a lot of testosterone before the levels drop. To avoid side effects from the hormonal surge, your doctor may suggest you take another kind of drug, called anti-androgens. These drugs block the ability of your prostate cancer cells to use androgens. Three common types of anti-androgen drugs are:

  • Bicalutamide (Casodex)
  • Flutamide (Eulexin)
  • Nilutamide (Nilandron)

You may take these before you start GnRH agents to avoid a hormone flare-up or if other hormone therapies stop working.

SOURCES:

American Cancer Society: "Prostate Cancer Overview," "Hormone (androgen deprivation) therapy for prostate cancer" and "Prostate Cancer Treatment (PDQ): Treatment Option Overview: Radiation Therapy."

American Urological Association: "Advanced Prostate Cancer."

Prostate Cancer Infolink: "Are all LHRH agonists 'just the same'?"

American Cancer Society web site. 

Reviewed by Brunilda Nazario on October 13, 2020

SOURCES:

American Cancer Society: "Prostate Cancer Overview," "Hormone (androgen deprivation) therapy for prostate cancer" and "Prostate Cancer Treatment (PDQ): Treatment Option Overview: Radiation Therapy."

American Urological Association: "Advanced Prostate Cancer."

Prostate Cancer Infolink: "Are all LHRH agonists 'just the same'?"

American Cancer Society web site. 

Reviewed by Brunilda Nazario on October 13, 2020

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How do you take hormone therapy for advanced prostate cancer?

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