With special occasions come special treats. But dining out can end in a battle with heartburn. This burning sensation in the chest is often accompanied by burping, a sore throat, sour stomach and problems with swallowing.

Person with hand on his/her chest in minor discomfort

From pizza night to popcorn at the movies, food and drink are common heartburn triggers, making you regret taking that extra slice hours after the last bite. But it’s not just dining out that can cause problems. Unsuspecting offenders, like your morning mug of coffee or even the tomato sauce in your homemade spaghetti with marinara, can bring on the burn.

Your Heartburn Starter Pack

If you are one of millions of heartburn sufferers, prevention is one of the best ways to keep it under control. Taking an over-the-counter H2 medication like Zantac 30-60 minutes before food or drink can help prevent heartburn before it occurs, so you enjoy life and all its savory, spicy and sweet moments. No compromise needed.

Family having dinner together

Let’s face it—the unexpected party invitation is bound to happen. But that doesn’t mean you have to face off with your favorite foods. And while many people reach for herbal teas and natural remedies for their heartburn symptoms, getting help from an effective H2 medication like Zantac can get you back to enjoying life fast.*

How H2s Help with Heartburn

If you’re a heartburn sufferer, learn the differences between the various treatment options, such as histamine 2 blockers (H2s), proton-pump inhibitors (PPIs) and antacids, so you don’t have to put your life on hold.

OTC Heartburn Treatment Options

Histamine 2 Blockers (H2 Blockers)

Used for:
Relieving and preventing heartburn associated with acid indigestion and sour stomach
Dosage for adults:
Take 1 tablet up to twice daily as needed. Do not take for more than 14 days unless advised by a doctor.
How it works:
Reduces stomach acid production
Onset of relief:
In as little as 30 minutes*
Duration of acid control:
Up to 12 hours**


Used for:
Relieving heartburn, acid indigestion, sour stomach and upset stomach associated with these symptoms
Dosage for adults:
Chew 2-4 tablets as symptoms occur. Do not take for more than 14 days unless advised by a doctor.
How it works:
Neutralizes stomach acid
Onset of relief:
In minutes
Duration of acid control:
1-3 hours

Proton-Pump Inhibitors (PPIs)

Used for:
Frequent heartburn occurring two or more days a week. Not intended for immediate relief of symptoms
Dosage for adults:
Take 1 capsule every day for 14 days. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor.
How it works:
Blocks acid production
Onset of relief:
Not intended for immediate relief. May take 1-4 days for full effect.
Duration of acid control:
Up to 24 hours (when used as a daily regimen)

PPIs are formulated to prevent heartburn but can take up to 24 hours when used as a daily regimen. Antacids offer relief, but it’s a short-term solution since relief only lasts 1-3 hours. Plus, antacids are effective only after heartburn occurs. An H2 medication like Zantac is different.

It works fast, in as little as 30 minutes,* and lasts up to 12 hours,** and can be used to treat and prevent* heartburn—great for when you want the freedom to enjoy your favorite meals however you want, whenever you want.

Group enjoying pizza night during tailgating - Football season.

With an H2 medication like Zantac handy, you can treat heartburn. When taken 30 to 60 minutes before eating or drinking, it can prevent symptoms before they start. So why not choose a heartburn treatment option that can do both?

Learn more about how an H2 can prevent and relieve heartburn symptoms.

For everyday heartburn relief that gives you greater flexibility and freedom, keep Zantac 75® in your medicine cabinet, or take it on the go so you can make it to that last-minute dinner invite. For extra heartburn help, choose Maximum Strength Zantac 150® (available unflavored or Cool Mint)—especially when second helpings are calling your name.

Learn more about getting help with your heartburn here.

*Prevents heartburn when taken 30-60 minutes before eating or drinking. Relieves heartburn in 30-60 minutes.
Based on product strength and directions.
**Controls acid for up to 12 hours, day or night.


National Institute of Diabetes and Digestive and Kidney Diseases: “Symptoms & Causes of GER & GERD.”

National Institute of Diabetes and Digestive and Kidney Diseases:
“Definition & Facts for GER & GERD.”

American College of Gastroenterology: "Acid Reflux: Overview." http://patients.gi.org/topics/acid-reflux/