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How do biologics treat RA?

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Biologics are genetically engineered proteins derived from human genes. They slow down, or "power down" parts of your immune system that help fuel inflammation, a central feature of rheumatoid arthritis.

Biologics are used to treat moderate to severe rheumatoid arthritis that has not responded to other treatments. They differ significantly from traditional drugs used to treat rheumatoid arthritis in that they target specific components of the immune system instead of broadly affecting many areas of it. Biologics may be used alone, but are commonly prescribed along with other rheumatoid arthritis medications.

From: Biologics for Rheumatoid Arthritis (RA) WebMD Medical Reference

SOURCES:

MedlinePlus: “Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients.”

Agency for Healthcare Research and Quality: “Rheumatoid Arthritis Medicines: A Guide for Adults.”

UpToDate for Patients: “Patient Information: Rheumatoid Arthritis Treatment.”

The Johns Hopkins Arthritis Center: “Rheumatoid Arthritis Treatment.”

American College of Rheumatology.

RxList.

FDA. News release. “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.”

Janssen Biotech Inc. News release, Roche.

Amgen Prescribing Information, Amjevita.

Reviewed by Melinda Ratini on September 02, 2018

SOURCES:

MedlinePlus: “Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients.”

Agency for Healthcare Research and Quality: “Rheumatoid Arthritis Medicines: A Guide for Adults.”

UpToDate for Patients: “Patient Information: Rheumatoid Arthritis Treatment.”

The Johns Hopkins Arthritis Center: “Rheumatoid Arthritis Treatment.”

American College of Rheumatology.

RxList.

FDA. News release. “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.”

Janssen Biotech Inc. News release, Roche.

Amgen Prescribing Information, Amjevita.

Reviewed by Melinda Ratini on September 02, 2018

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What are the side effects of biologics that treat RA?

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