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How does Rituxan treat RA?

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Rituximab (Rituxan) is used to treat rheumatoid arthritis that has not improved with TNF-blockers, such as etanercept (Enbrel), adalimumab (Humira), or Infliximab (Remicade). Rituxan is an antibody protein that works by targeting and reducing the number of specialized white blood cells, called B cells, in the blood. Rituxan is given as two intravenous infusions, two weeks apart. You may get repeat courses of Rituxan after four to six months.

Rituxan's most common side effects are fever, chills, nausea, headache, and low levels of white blood cells.

From: Biologics for Rheumatoid Arthritis (RA) WebMD Medical Reference

SOURCES:

MedlinePlus: “Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients.”

Agency for Healthcare Research and Quality: “Rheumatoid Arthritis Medicines: A Guide for Adults.”

UpToDate for Patients: “Patient Information: Rheumatoid Arthritis Treatment.”

The Johns Hopkins Arthritis Center: “Rheumatoid Arthritis Treatment.”

American College of Rheumatology.

RxList.

FDA. News release. “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.”

Janssen Biotech Inc. News release, Roche.

Amgen Prescribing Information, Amjevita.

Reviewed by Melinda Ratini on September 02, 2018

SOURCES:

MedlinePlus: “Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients.”

Agency for Healthcare Research and Quality: “Rheumatoid Arthritis Medicines: A Guide for Adults.”

UpToDate for Patients: “Patient Information: Rheumatoid Arthritis Treatment.”

The Johns Hopkins Arthritis Center: “Rheumatoid Arthritis Treatment.”

American College of Rheumatology.

RxList.

FDA. News release. “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.”

Janssen Biotech Inc. News release, Roche.

Amgen Prescribing Information, Amjevita.

Reviewed by Melinda Ratini on September 02, 2018

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How does Simponi or Simponi Aria treat RA?

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