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How do biologic drugs help rheumatoid arthritis?

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Biologic response modifiers are a type of disease-modifying anti-rheumatic drug. They target the part of the immune system response that leads to inflammation and joint damage. They can't cure RA, but they may slow the progression of the disease or help put it into remission. If your doctor prescribes one, you'll likely take it in combination with methotrexate. You get them by injection or by IV.

  • Abatacept (Orencia)
  • Adalimumab (Humira), adalimumab-atto (Amjevita)
  • Anakinra (Kineret)
  • Certolizumab pegol (Cimzia)
  • Etanercept (Enbrel), etanercept-szzs (Erelzi)
  • Golimumab (Simponi)
  • Infliximab-dyyb (Inflectra)
  • Rituximab (Rituxan)
  • Sarilumab (Kevzara)
  • Tocilizumab (Actemra)

From: Rheumatoid Arthritis Drug Guide WebMD Medical Reference

SOURCES: 

American College of Rheumatology: "Rheumatoid Arthritis." Amgen Prescribing Information, Amjevita. Arthur Kavanaugh, MD, rheumatologist; professor of medicine, University of California at San Diego. Arthritis Foundation: "Drug Guide." eMedicine Health: "Rheumatoid Arthritis." FDA: "Therapeutics for Rheumatoid Arthritis." “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.” Medscape: "FDA Approves Orencia." Simponi.  Singh, R. vol 17: pp 274-279. WebMD Medical News: "New Rheumatoid Arthritis Drugs Work Well." "Celebrex Linked to Heart Attacks." WebMD Medical Reference from Healthwise: "Rheumatoid Arthritis -- Medications." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Arthritis Medicines Overview," "Steroids to Treat Arthritis," "Disease-Modifying Medications," "Biologics."










Current Opinion in Rheumatology;

Reviewed by Melinda Ratini on September 04, 2018

SOURCES: 

American College of Rheumatology: "Rheumatoid Arthritis." Amgen Prescribing Information, Amjevita. Arthur Kavanaugh, MD, rheumatologist; professor of medicine, University of California at San Diego. Arthritis Foundation: "Drug Guide." eMedicine Health: "Rheumatoid Arthritis." FDA: "Therapeutics for Rheumatoid Arthritis." “FDA approves Inflectra, a biosimilar to Remicade.” "Prescribing Information, Infliximab-dyyb (Inflectra)." “FDA approves Amjevita, a biosimilar to Humira.” Medscape: "FDA Approves Orencia." Simponi.  Singh, R. vol 17: pp 274-279. WebMD Medical News: "New Rheumatoid Arthritis Drugs Work Well." "Celebrex Linked to Heart Attacks." WebMD Medical Reference from Healthwise: "Rheumatoid Arthritis -- Medications." WebMD Medical Reference provided in collaboration with Cleveland Clinic: "Arthritis Medicines Overview," "Steroids to Treat Arthritis," "Disease-Modifying Medications," "Biologics."










Current Opinion in Rheumatology;

Reviewed by Melinda Ratini on September 04, 2018

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What should you do before you start taking a biologic drug for rheumatoid arthritis?

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