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What are the side effects of hydroxychloroquine and sulfasalazine in treating rheumatoid arthritis?

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Hydroxychloroquine (Plaquenil) and sulfasalazine (Azulfidine) are used for mild rheumatoid arthritis. They are not as powerful as other disease-modifying antirheumatic drugs, but they usually cause fewer side effects. In rare cases, hydroxychloroquine (Plaquenil) can have side effects that affect the eyes, so people who take this medicine should see an ophthalmologist at least once a year.

SOURCES:

American College of Rheumatology Ad Hoc Committee on Clinical Guidelines, Guidelines for the management of rheumatoid arthritis: 2002 update, , 2002. Arthritis and Rheumatism

Harris, E., , W.B. Saunders, 2005.  Kelley's Textbook of Rheumatology, 7th edition

Klippel, John H., , 12th edition, Arthritis Foundation, 2001.  Primer on the Rheumatic Diseases

Maetzel A., , December 1998.  Journal of Rheumatology

RxList.com: Patient Drug Information. 

Reviewed by David Zelman on October 13, 2019

SOURCES:

American College of Rheumatology Ad Hoc Committee on Clinical Guidelines, Guidelines for the management of rheumatoid arthritis: 2002 update, , 2002. Arthritis and Rheumatism

Harris, E., , W.B. Saunders, 2005.  Kelley's Textbook of Rheumatology, 7th edition

Klippel, John H., , 12th edition, Arthritis Foundation, 2001.  Primer on the Rheumatic Diseases

Maetzel A., , December 1998.  Journal of Rheumatology

RxList.com: Patient Drug Information. 

Reviewed by David Zelman on October 13, 2019

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