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Why do biologic drugs seem to work for a while then become ineffective?

ANSWER

t’s not clear why. If it happens to you, tell your doctor. He or she will probably switch you to another biologic or add another type of rheumatoid arthritis drug, like methotrexate or sulfasalazine, so your treatment works better.

SOURCES:

Patience White, MD, chief public health officer, Arthritis Foundation.

Alan Friedman, MD, spokesman, American College of Rheumatology.

American College of Rheumatology: "Biologic Treatments for Rheumatoid Arthritis," "Anti-TNF," "Tocilizumab."

Arthritis Foundation: "Drug Guide: Biologics."

FDA: "FDA approves Amjevita, a biosimilar to Humira."

News Release, FDA.

Reviewed by Minesh Khatri on September 15, 2019

SOURCES:

Patience White, MD, chief public health officer, Arthritis Foundation.

Alan Friedman, MD, spokesman, American College of Rheumatology.

American College of Rheumatology: "Biologic Treatments for Rheumatoid Arthritis," "Anti-TNF," "Tocilizumab."

Arthritis Foundation: "Drug Guide: Biologics."

FDA: "FDA approves Amjevita, a biosimilar to Humira."

News Release, FDA.

Reviewed by Minesh Khatri on September 15, 2019

NEXT QUESTION:

Do biologics work for everyone who has rheumatoid arthritis (RA)?

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