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How do atypical antipsychotics treat delusional disorder?

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Atypical anti-psychotics are newer drugs that appear to be effective in treating the symptoms of delusional disorder with fewer movement-related side effects than older, conventional anti-psychotics. They work by blocking dopamine and serotonin receptors in the brain. (Like dopamine, serotonin is a neurotransmitter believed to be involved in delusional disorder.) These drugs include: aripiprazole (Abilify), aripiprazole lauroxil (Aristada), asenapine (Saphris), clozapine (Clozaril), iloperidone (Fanapt), lurasidone (Latuda),  paliperidone (Invega Sustenna), paliperidone palmitate (Invega Trinza), quetiapine (Seroquel), risperidone (Risperdal), olanzapine (Zyprexa), and ziprasidone (Geodon). 

Newer atypical antipsychotics : these include brexpiprazole (Rexulti) and cariprazine (Vraylar).

From: Delusions and Delusional Disorder WebMD Medical Reference

SOURCES:

Intelihealth: "Delusional Disorder."

Disorders.org: "Delusional."

Medscape: "Delusional Disorder."

Diagnostic and Statistical Manual of Mental Disorders IV: "Delusional Disorder."

 

Reviewed by Joseph Goldberg on December 19, 2018

SOURCES:

Intelihealth: "Delusional Disorder."

Disorders.org: "Delusional."

Medscape: "Delusional Disorder."

Diagnostic and Statistical Manual of Mental Disorders IV: "Delusional Disorder."

 

Reviewed by Joseph Goldberg on December 19, 2018

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What other medications might doctors use to treat delusional disorder?

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