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Is there anyone who shouldn’t take lurasidone?

ANSWER

Elderly people with dementia-related psychosis should not take this drug: it can raise the chances of stroke or death. It can cause sleepiness and lightheadedness, making a fall more likely. It can make it hard to swallow, which could lead to choking.

SOURCES:

National Alliance on Mental Illness: “Lurasidone (Latuda).”

U.S. National Library of Medicine, DailyMed: “Latuda – lurasidone hydrochloride tablet, film coated,” “Toxnet: “Lactmed: Lurasidone.”

  : “The Incidence of Akathisia in the Treatment of Schizophrenia with Aripiprazole, Asenapine and Lurasidone: A Meta-Analysis.” Current Neuropharmacology

BJPsych Bulletin : “Lurasidone: a novel antipsychotic agent for the treatment of schizophrenia and bipolar depression.”

Therapeutics and Clinical risk Management : “Clinical potential of lurasidone in the management of schizophrenia.”

Nursing 2019 : “Monitoring for drug-induced movement disorders.”

Neuropsychiatric Disease and Treatment : “Antipsychotic-associated weight gain: management strategies and impact on treatment adherence.”

Annals of General Psychiatry: “Weight changes before and after lurasidone treatment: a real-world analysis using electronic health records.”

Latuda: “Side Effects of Latuda.”

StatPearls: “Lurasidone.”

Reviewed by Jennifer Casarella on November 25, 2019

SOURCES:

National Alliance on Mental Illness: “Lurasidone (Latuda).”

U.S. National Library of Medicine, DailyMed: “Latuda – lurasidone hydrochloride tablet, film coated,” “Toxnet: “Lactmed: Lurasidone.”

  : “The Incidence of Akathisia in the Treatment of Schizophrenia with Aripiprazole, Asenapine and Lurasidone: A Meta-Analysis.” Current Neuropharmacology

BJPsych Bulletin : “Lurasidone: a novel antipsychotic agent for the treatment of schizophrenia and bipolar depression.”

Therapeutics and Clinical risk Management : “Clinical potential of lurasidone in the management of schizophrenia.”

Nursing 2019 : “Monitoring for drug-induced movement disorders.”

Neuropsychiatric Disease and Treatment : “Antipsychotic-associated weight gain: management strategies and impact on treatment adherence.”

Annals of General Psychiatry: “Weight changes before and after lurasidone treatment: a real-world analysis using electronic health records.”

Latuda: “Side Effects of Latuda.”

StatPearls: “Lurasidone.”

Reviewed by Jennifer Casarella on November 25, 2019

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