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What is a serious side effects of long-acting injectable drugs for schizophrenia?

ANSWER

A serious side effect called post-injection delirium sedation syndrome affects less than 1% of people after taking olanzapine pamoate (Zyprexa Relprevv), a long-acting medicine. It can cause dizziness, confusion, and movements you can't control, and it usually happens within an hour of getting a shot. Because of this small risk, you'll need to stay at your doctor's office for at least 3 hours after your shot so doctors can watch you for side effects.

SOURCES:

National Institute of Mental Health.

News release, University of California, Los Angeles.

FDA.

News release, Janssen Pharmaceuticals Inc.

UpToDate: "Pharmacotherapy for schizophrenia: Long-acting injectable antipsychotic drugs."

Valenstein, M. , 2004. Schizophrenia Bulletin

Osborne, R. , April 2012. Health and Quality of Life Outcomes

National Alliance on Mental Illness: "Mental Health Medications."

Rosenheck, R. , March 2011. New England Journal of Medicine

Brissos, S. , October 2014. Therapeutic Advances in Pharmacology

Reviewed by Joseph Goldberg on July 17, 2018

SOURCES:

National Institute of Mental Health.

News release, University of California, Los Angeles.

FDA.

News release, Janssen Pharmaceuticals Inc.

UpToDate: "Pharmacotherapy for schizophrenia: Long-acting injectable antipsychotic drugs."

Valenstein, M. , 2004. Schizophrenia Bulletin

Osborne, R. , April 2012. Health and Quality of Life Outcomes

National Alliance on Mental Illness: "Mental Health Medications."

Rosenheck, R. , March 2011. New England Journal of Medicine

Brissos, S. , October 2014. Therapeutic Advances in Pharmacology

Reviewed by Joseph Goldberg on July 17, 2018

NEXT QUESTION:

How do the side effects of daily pills differ from those associated with long-acting injectable drugs for schizophrenia?

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