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What are symptoms of neuroleptic malignant syndrome caused by older and newer antipsychotics for schizophrenia?

ANSWER

Both older and newer antipsychotics may cause a rare condition called neuroleptic malignant syndrome. Symptoms include:

  • High fever
  • Sweating
  • Big swings in blood pressure
  • Muscle stiffness

SOURCES:

Agency for Healthcare Research and Quality: "Antipsychotic Medicines for Treating Schizophrenia and Bipolar Disorder."

UpToDate: "Pharmacotherapy for schizophrenia: Long-acting injectable antipsychotic drugs."

HelpGuide.org: "Schizophrenia Treatment & Recovery."

Cleveland Clinic: "Schizophrenia."

National Alliance on Mental Illness: "Introduction: Mental Health Medications and Tardive Dyskinesia."

Reviewed by Jennifer Casarella on November 25, 2019

SOURCES:

Agency for Healthcare Research and Quality: "Antipsychotic Medicines for Treating Schizophrenia and Bipolar Disorder."

UpToDate: "Pharmacotherapy for schizophrenia: Long-acting injectable antipsychotic drugs."

HelpGuide.org: "Schizophrenia Treatment & Recovery."

Cleveland Clinic: "Schizophrenia."

National Alliance on Mental Illness: "Introduction: Mental Health Medications and Tardive Dyskinesia."

Reviewed by Jennifer Casarella on November 25, 2019

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What symptoms are older antipsychotic medicines likely to cause, compared to newer ones, when part of schizophrenia treatment?

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