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What medications treat neuroleptic malignant syndrome (NMS)?

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Your doctor will first take you off the drug that caused this syndrome. Often, people with NMS get treatment in a hospital intensive care unit. The goal is to bring down your fever and give you fluids and nutrition.

Medications used to treat NMS include:

  • Drugs that relax tight muscles, such as dantrolene (Dantrium)
  • Parkinson's disease drugs that make your body produce more dopamine, such as amantadine (Symmetrel) or bromocriptine (Parlodel)

SOURCES:

Kateon, H. , published online September 2013. Mental Health Clinician

Merck Manual Professional Version: "Neuroleptic Malignant Syndrome."

National Institute of Neurological Disorders and Stroke: "NINDS Neuroleptic Malignant Syndrome Information Page."

National Organization for Rare Disorders: "Neuroleptic Malignant Syndrome."

OrphaNet: "Neuroleptic Malignant Syndrome."

Reviewed by Jennifer Casarella on December 4, 2019

SOURCES:

Kateon, H. , published online September 2013. Mental Health Clinician

Merck Manual Professional Version: "Neuroleptic Malignant Syndrome."

National Institute of Neurological Disorders and Stroke: "NINDS Neuroleptic Malignant Syndrome Information Page."

National Organization for Rare Disorders: "Neuroleptic Malignant Syndrome."

OrphaNet: "Neuroleptic Malignant Syndrome."

Reviewed by Jennifer Casarella on December 4, 2019

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How can electroconvulsive therapy help with treating neuroleptic malignant syndrome (NMS)?

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