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Which antipyschotics make you gain weight?

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Some antipsychotic drugs are more likely than others to cause weight gain. The risk is highest with clozapine (Clozaril, FazaClo) and olanzapine (Zyprexa). Chlorpromazine has a high to medium risk, while paliperidone, quetiapine, and risperidone have a medium risk.

Antipsychotics with lower risk of weight gain are:

But everyone is different. You might gain a lot, a little, or no weight or even lose weight when taking an antipsychotic. It all depends on what you eat, how much you exercise, and your genes.

  • Aripiprazole (Abilify)
  • Asenapine (Saphris)
  • Brexipiprazole (Rexulti)
  • Haloperidol (Haldol)
  • Lurasidone (Latuda)
  • Ziprasidone (Geodon)

SOURCES:

British Association of Psychopharmacology: “Antipsychotic Medication and Weight Gain.”

Neuropsychiatric Disease and Treatment : “Antipsychotic-associated weight gain: management strategies and impact on treatment adherence.”

Mayo Clinic: “Bipolar Medications and Weight Gain.”

National Alliance on Mental Illness: “Clozapine (Clozaril And FazaClo).”

Reviewed by Smitha Bhandari on April 14, 2020

SOURCES:

British Association of Psychopharmacology: “Antipsychotic Medication and Weight Gain.”

Neuropsychiatric Disease and Treatment : “Antipsychotic-associated weight gain: management strategies and impact on treatment adherence.”

Mayo Clinic: “Bipolar Medications and Weight Gain.”

National Alliance on Mental Illness: “Clozapine (Clozaril And FazaClo).”

Reviewed by Smitha Bhandari on April 14, 2020

NEXT QUESTION:

How do you keep from gaining weight on an antipsychotic?

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