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How can genes play a role in the link between eczema and allergies?

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Researchers have found that some people with eczema have a gene flaw that causes a lack of a type of protein, called filaggrin, in their skin. It helps form the protective outer layer of skin and keeps out germs and more. A lack of filaggrin dries out and weakens that skin barrier. This makes skin vulnerable to irritants, like soaps and detergents, and makes it easier for allergens to enter the body. Scientists say that makes people more sensitive to those allergens and even some foods.

SOURCES:

U.S. Department of Health and Human Services: "Atopic Dermatitis."

Asthma and Allergy Foundation of America: "Atopic Dermatitis (Eczema.)"

American Academy of Dermatology: "Atopic Dermatitis: Who Gets and Causes."

EczemaNet: "Types of Eczema: Atopic Dermatitis."

PubMedHealth: Allergies."

Eczema.org: "Dry skin and atopic eczema: An Update on the Filaggrin Story... What Does It Mean to You?"

Sandilands, A. May 1, 2009. Journal of Cell Science;

National Eczema Association: "Research Confirms Genetic Skin Barrier Linked to Eczema."

American Academy of Dermatology: "What is Eczema?"

Reviewed by Stephanie S. Gardner on April 10, 2018

SOURCES:

U.S. Department of Health and Human Services: "Atopic Dermatitis."

Asthma and Allergy Foundation of America: "Atopic Dermatitis (Eczema.)"

American Academy of Dermatology: "Atopic Dermatitis: Who Gets and Causes."

EczemaNet: "Types of Eczema: Atopic Dermatitis."

PubMedHealth: Allergies."

Eczema.org: "Dry skin and atopic eczema: An Update on the Filaggrin Story... What Does It Mean to You?"

Sandilands, A. May 1, 2009. Journal of Cell Science;

National Eczema Association: "Research Confirms Genetic Skin Barrier Linked to Eczema."

American Academy of Dermatology: "What is Eczema?"

Reviewed by Stephanie S. Gardner on April 10, 2018

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Are defects in the skin or blood cells linked to eczema and allergies?

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