Drug eruptions (dermatitis medicamentosa). Diagnosing drug eruptions has become a common experience to practitioners in all branches of modern medicine. The profusion of drugs now available, the continuous influx of new drugs, and the capability of drugs to cause actions different from or in addition to their pharmacologically desirable actions make adverse cutaneous reactions an inevitable fact of modern medical practice. The kinds of cutaneous reactions are varied. Exanthems (erythematous, morbilliform or maculopapular), urticaria (hive-like), papulosquamous ( bumps with scale), pustular, purpuric (bruise-like), bullous (blisters), lichenoid (purple, flat-topped papules), fixed drug eruptions and erythema multiforme (target lesions) are the most common. Constitutional symptoms of low-grade fever and malaise may be associated with such drug eruptions. Morbilliform eruptions from ampicillin are more frequently seen in children with infectious mononucleosis.
Color Atlas of Pediatric Dermatology Samuel Weinberg, Neil S. Prose, Leonard Kristal Copyright 2008, 1998, 1990, 1975, by the McGraw-Hill Companies, Inc. All rights reserved.
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