Serum Sickness

Medically Reviewed by Stephanie S. Gardner, MD on April 26, 2022

photo of serum sickness on man's back

Serum sickness is a delayed hypersensitivity reaction that is similar to an allergy. It happens when your body reacts to certain medications or antiserums. Typical reactions include a rash, fever, and joint pain. The sickness usually clears up once the medication is stopped.

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