Smoking May Raise Psoriasis Risk

Study Shows Exposure to Secondhand Smoke During Pregnancy or Childhood Also Ups Risk

From the WebMD Archives

Oct. 29, 2007 -- Smoking not only takes its toll on your body from the inside, but a new study shows it also affects how your skin looks and feels on the outside.

Researchers found that smoking increases the risk of psoriasis, which causes symptoms such as inflammation, redness, itching, and scaling of the skin.

The study shows the risk of psoriasis was 78% higher among current smokers compared with people who had never smoked and 37% higher among smokers who had quit previously.

Researchers say the results suggest that quitting smoking may help alleviate the symptoms of psoriasis in smokers with the skin disease.

"These findings, along with well-established hazardous health effects of smoking, provide clear incentives for smoking cessation in those at risk for and suffering from psoriasis," writes researcher Hyon K. Choi, MD, DrPH, of Harvard Medical School, and colleagues in the American Journal of Medicine.

Smoking Linked to Psoriasis

Researchers looked at the relationship between smoking and psoriasis in more than 78,500 female registered nurses who took part in the Nurses Health Study II. The women were followed for 14 years, and during that period 887 cases of psoriasis were reported.

Researchers measured lifetime smoking exposure in pack-years. A pack-year is the number of packs smoked per day multiplied by the number of years a person has smoked.

The results showed that smoking not only increased the risk of psoriasis, but heavier smoking increased that risk further. For example, compared with women who never smoked, the risk of psoriasis was 60% higher for those with a smoking history of 11-20 pack-years and more than two times high for those with 21 or more pack-years of smoking.

Exposure to secondhand smoke during pregnancy or childhood also increased the risk of psoriasis (21% and 18% increased risk respectively).

Researchers found the risk of psoriasis decreased after quitting smoking, with the risk of psoriasis among former smokers comparable to nonsmokers 20 years after quitting.

WebMD Health News Reviewed by Louise Chang, MD on October 29, 2007


SOURCES: Setty, A. American Journal of Medicine, November 2007; vol 120: 954-959. News release, Elsevier.

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